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Salk Institute Identifies Affective Pain Circuit, Eyes Migraine Drugs for Therapy

They aim to test CGRP antagonists in translational studies to silence the thalamic pathway that drives emotional responses to pain without dulling sensation.

4 ARTICLES

1h ago

Frequent Gabapentin Use Tied to Higher Dementia and Cognitive Impairment Risk

3 ARTICLES

7h ago

Polysaccharide Coating Significantly Improves Adhesion of Liver Progenitor Cells

5 ARTICLES

8h ago

Single CRISPR Treatment Lets Mice Produce Weight-Loss Drug for Over Six Months

8 ARTICLES

10h ago

Modified Herpes Virus Plus Nivolumab Induces Tumor Regression in Advanced Melanoma

4 ARTICLES

21h ago

UCSF Model Maps Genetic Drivers of Tau Vulnerability and Resilience in Alzheimer’s

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4 ARTICLES

yesterday

Small-Molecule Precursors Restore CoQ10 and Reverse Neurological Decline in HPDL Deficiency

3 ARTICLES

last wk.

Benzaldehyde Disrupts Protein Interface to Thwart Pancreatic Cancer Resistance and Metastasis

3 ARTICLES

last wk.

Liraglutide Pilot Study Halves Chronic Migraine Days, Paves Way for Randomized Trials

5 ARTICLES

last wk.

Scientists Harness Mouth’s GAS6-AXL Pathway to Reduce Skin Scarring

4 ARTICLES

last wk.

MLi-2 Kinase Inhibitor Fully Restores Neuronal Cilia and Promotes Recovery in a Parkinson’s Mouse Model

3 ARTICLES

last wk.

Repurposed Psoriasis Drug Restores Brain Function in Vascular Dementia Mice

3 ARTICLES

last wk.

AP1M1 Knockout Validated to Enhance Antisense Drug Delivery, Guiding Broader RNA Therapy Development

3 ARTICLES

last wk.

Amgen Advances Monthly Obesity Drug to Phase 3 After 20% Weight Loss in Mid-Stage Trial

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Medicine

Salk Institute Identifies Affective Pain Circuit, Eyes Migraine Drugs for Therapy

Frequent Gabapentin Use Tied to Higher Dementia and Cognitive Impairment Risk

Polysaccharide Coating Significantly Improves Adhesion of Liver Progenitor Cells

Single CRISPR Treatment Lets Mice Produce Weight-Loss Drug for Over Six Months

Modified Herpes Virus Plus Nivolumab Induces Tumor Regression in Advanced Melanoma

UCSF Model Maps Genetic Drivers of Tau Vulnerability and Resilience in Alzheimer’s

Small-Molecule Precursors Restore CoQ10 and Reverse Neurological Decline in HPDL Deficiency

Benzaldehyde Disrupts Protein Interface to Thwart Pancreatic Cancer Resistance and Metastasis

Liraglutide Pilot Study Halves Chronic Migraine Days, Paves Way for Randomized Trials

Scientists Harness Mouth’s GAS6-AXL Pathway to Reduce Skin Scarring

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MLi-2 Kinase Inhibitor Fully Restores Neuronal Cilia and Promotes Recovery in a Parkinson’s Mouse Model

Repurposed Psoriasis Drug Restores Brain Function in Vascular Dementia Mice

AP1M1 Knockout Validated to Enhance Antisense Drug Delivery, Guiding Broader RNA Therapy Development

3D-Bioprinted Human Pancreatic Islets Enter Preclinical Animal Trials

Dormant Vitamin A Gene Switch Restores Ear Regeneration in Mice

Fungus-Derived Asperigimycins Show Potent Activity Against Leukemia Cells

Vitamin C Reactivates Growth Genes to Thicken Aging Skin

HIV Gene Therapy Harnesses Viral RNA to Lock Virus Into Dormant State

Portable Device Allows Hospitals to Make Personalized Gene Therapies On Demand

Amgen Advances Monthly Obesity Drug to Phase 3 After 20% Weight Loss in Mid-Stage Trial

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