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Tau Neutralizes HSV-1 in Human Neuron Cultures, Pointing to Antiviral Roots of Alzheimer’s Features

The findings propose a brain host-defense role for tau that now needs confirmation beyond cell cultures.

Sanofi Ends PPMS Bid After Tolebrutinib Fails Phase 3 as FDA Delays Review for nrSPMS

Praxis Relutrigine Study Halted Early for Efficacy as FDA Review Meeting Set

Bristol Myers Delays ADEPT-2 Alzheimer’s Psychosis Readout to 2026 After Site Irregularities

New Review Positions Camelid Nanobodies as a Promising Path for Brain Therapies

Study Finds PU.1-Low, CD28-Positive Microglia Curb Alzheimer’s Damage

Engineered Nanoparticles Restore Blood–Brain Barrier and Clear Amyloid in Alzheimer’s Mice

Nanoparticles Restore Brain Barrier, Reverse Alzheimer’s Signs in Mice

Inhaled CBD Dampens Brain Inflammation in Alzheimer’s Mouse Model

Lancet Series Calls for Health-System Overhaul to Deliver New Alzheimer’s Blood Tests and Antibody Drugs

Neuron-Microglia Signal Near Plaques Emerges as a Potential Alzheimer’s Target

Alzheimer’s Study Ties Familial SORL1 Variant to Fewer, Weaker Brain Exosomes

Rapport Seizure Drug Posts Strong Phase 2 Signal as Company Plans Phase 3

Chronic Neuron Overactivity in Mice Triggers Parkinson’s-Like Dopamine Cell Loss

Tumor-Induced Nerve Injury Identified as Driver of Anti–PD-1 Resistance

Early Smell Loss in Alzheimer’s Driven by Microglial Axon Removal

Engineered Antibody Transport Vehicle Boosts Alzheimer’s Antibody Delivery to Mouse Brain

Dietary Compounds Restore Energy and Protein Clearance in Aging Neurons

Metformin Requires Hypothalamic Rap1 Inactivation to Lower Blood Sugar

UCSF Validates GPCR ADGRG1’s Role in Clearing Alzheimer’s Plaques, Paving Way for New Therapies