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Research

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APOE4 Triggers Vascular Scarring and Protein Build‑Up in Human Brain Models

Blocking TGF-β restored pericyte coverage in mice, signaling a preclinical path to target APOE4-driven vascular injury.

FDA Approves Rasonque, an Oral KRAS Inhibitor, for Metastatic Pancreatic Cancer

TOFA Boosts Fat Burning in Mice While Preserving Muscle

GLP-1 Drugs Reshape Obesity Care

New Blood Biomarkers Differentiate Alzheimer’s Risk by Disease Stage

Study Finds Small Rise in Smell and Taste Diagnoses Among People on GLP‑1 Diabetes Drugs

Fibroblasts Explain Why Lung Cancer Subtypes Respond Differently to Anti‑Angiogenic Drugs

Copper Compound Restores Brain Clearance Pump and Cuts Alzheimer’s Proteins in Mice

Virtual Reality Test Predicts Short-Term Brain Shrinkage in Healthy Adults

Brazil Moves to Tighten Rules on GLP‑1 Weight‑Loss Pens as Demand Surges

Experimental Drug Elraglusib Extends Survival in Phase 2 Pancreatic Cancer Trial

NIH Identifies DFNZ, a Nitazene Opioid That Eased Pain in Rats Without Breathing Risks

Metformin Lowers Blood Sugar Through Brain Circuit, Mouse Study Finds

TIE2 Identified as Drug Target in Brain Cavernous Malformations After Mouse Study Stops New Lesions

Photoreceptor Apoptosis Shown Reversible via Mitophagy in Mouse Models

Study Identifies Immune Off Switch Behind Why Pain Lasts Longer in Women

Massive Multi-Ancestry Study Maps Tissue-Specific Drivers of Type 2 Diabetes

Restoring NAD+ Reverses Alzheimer’s Signs in Mice, Study Finds

Vagus Nerve Repair Slows Cardiac Ageing in Preclinical Study

Tau Neutralizes HSV-1 in Human Neuron Cultures, Pointing to Antiviral Roots of Alzheimer’s Features