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Study Finds TGF-β Builds Dual Immune Barrier in Metastatic Colorectal Cancer

The Nature Genetics paper highlights targetable signals to boost checkpoint therapy in liver metastases.

Triple Therapy Counters Endocrine Resistance in ER+ Breast Cancer in Preclinical Study

Targeted Nanoparticles Help Checkpoint Drugs Erase Ovarian Tumors in Mice

Study Ties CGRP–RAMP1 Signaling to GI Tumor Growth, Pointing to Repurposed Migraine Therapies

Takeda Strikes $11 Billion-Plus Oncology Deal With Innovent, Pays $1.2 Billion Upfront

UC San Diego AI Identifies PRKAB1 Target to Reprogram Colon Cancer Stem Cells

mRNA COVID Vaccination Linked to Longer Survival With Cancer Immunotherapy, Data Presented at ESMO

HSF1-Driven Autophagy Found to Undercut Proteasome Drugs in AML, Preclinical Combo Shows Benefit

Tumor CRATERs Flag T-Cell Killing Hotspots and Track With Immunotherapy Response

Endoxifen Add-On Restores Tamoxifen Levels in Poor Metabolizers, Phase 1/2 Trial Finds

Study Reveals How Tumor Bacteria Induce Quiescence to Thwart Cancer Treatment

Google and Yale Release 27B-Parameter Cell AI After Lab Confirms Interferon-Conditional Antigen Boost

Niraparib Add-On Slows Progression in Advanced Prostate Cancer, Phase III Trial Shows

Engineered CAR-T Cells Target PD-L1 to Deliver IL-12 at Tumors, Showing Solid-Tumor Gains in Mice

Genmab to Buy Merus for $8 Billion to Secure Petosemtamab Cancer Drug

Mayo-Led Study Links PNPLA3 Variant to Chemotherapy-Related Liver Injury in Colorectal Liver Metastases

KAIST Links Enlarged Cancer Nuclei to Replication Stress That Slows Metastasis in Mice

UC Researchers Target Hsp70 to Counter Pancreatic Cancer Immunosuppression With Preclinical Nanovesicle Therapy

ALK7 Identified as Driver of Pancreatic Cancer’s Bloodstream Entry in Preclinical Study

Oncopathology Pioneer Dr Anita Borges Dies at 78 While Teaching in Gorakhpur