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Daraxonrasib Doubles Survival in Previously Treated Advanced Pancreatic Cancer

The pill uses a molecular‑glue action on KRAS and has triggered FDA expanded access along with an expedited review pathway.

Spatial Map of Tumor Macrophages Shows Some Eat Cancer While Others Feed It

Tumor Inflammation Drives Early Resistance to KRAS Drugs, Study Shows

Akari’s AKTX-101 Shows Preclinical Synergy With KRAS Inhibitor as Stock Soars

Asthma Drug Montelukast Restores Checkpoint Response in Preclinical Cancer Models

Aging Drives Breast Cancer Metastasis Through RAGE, Study Finds

Ascites Lipids Help Ovarian Cancer Evade Cell Death, Duke Study Finds

Inhibrx Combo Shows 44% Response vs 21% With Pembrolizumab Alone in First-Line Head and Neck Cancer

Preclinical Combo Reprograms Tumor Immunity to Overcome Colorectal Cancer Resistance

CRISPR Enzyme Cas12a2 Selectively Destroys Cells Based on RNA in Lab Tests

FDA Clears Vepdegestrant, First PROTAC Cancer Drug, for ESR1‑Mutated Breast Cancer

New CAR-T Designs Deliver Low-Dose Remissions and Expose a Senescence Risk

Single CAR T Infusion Clears Residual Disease in High-Risk Smoldering Myeloma Trial

Theriva’s VCN-01 Extends Survival in Phase 2b Pancreatic Cancer Trial, Paving Way to Phase 3

Experimental Drug Elraglusib Extends Survival in Phase 2 Pancreatic Cancer Trial

IDEAYA Combo Doubles Progression-Free Survival in Uveal Melanoma Trial

Cancer Study Maps Brain Metastasis Switch and Identifies Ibudilast as a Repurposing Candidate

Androgen Signaling Drives Lethal Pediatric Ependymoma, Study Finds

New RNA Splicing Readout Charts Cancer-Wide Programs, Points to About 120 Potential Targets

Ultrasound-Activated Nanobubbles Break Tumor Barriers in Mouse Study