Computational Biology

Bioinformatics Machine Learning Data Analysis Artificial Intelligence Data Science Genomics Modeling Techniques Modeling Simulation Models Genome Design

AlphaFold3-Guided ContactSeek Rewrites Base Editors to Cut Off-Target Edits

It offers a fast route to safer base editors by using AlphaFold3 to map and redesign protein–DNA contacts.

3D Genome Rearrangement Found in Alzheimer's Brain Cells, Study Shows

Researchers Deliver 4D Whole-Cell Simulation That Replicates Minimal Bacterium’s Full Life Cycle

Evo 2, an Open DNA Foundation Model, Debuts in Nature

Social Partners' Genes Sway Gut Microbiomes, Rat Megastudy Finds

AI Model popEVE Delivers Proteome-Wide Severity Scores for Rare-Disease Diagnosis

DeepMind–Yale AI Identifies Drug Candidate That Raises Tumor Antigen Signals by 50% in Lab Tests

UW Engineers Program Proteins to Make Logic‑Gated Decisions for Targeted Drug Delivery

Scripps Team Designs Ultra-Stable Synthetic Membrane Proteins to Decode Common Folding Motif

IIT Madras–ICMR Team Identifies ALT1 as New Antifungal Target in Candida Albicans

UCLA Tool Charts Thousands of mRNA Stability Variants Linked to Autoimmune Risk

Mount Sinai Team Publishes MARQO, AI Pipeline for Faster Whole-Slide Cancer Tissue Analysis

Yale’s ChronODE Pinpoints Gene Activation Windows in the Developing Brain

AI-Informed Pipeline Accelerates Bi-Specific CAR-T Design and Clears Tumors in Mice

UNAM Morelia Wins Top CAMDA 2025 Trophy for Data-Driven Antibiotic-Resistance Research

BigHorn Tool Reveals Coordinated Transcriptional and Post-Transcriptional Control by lncRNAs

Brain Aging Clock Uncovers 453 Rejuvenating Compounds and Validates Three in Aged Mice

Computational Study Maps When Sleep Strengthens Synaptic Connections

Artificial Enzymes Designed by Computers Rival Natural Catalysts

moPepGen Graph Algorithm Quadruples Protein Variant Detection in Tumor Samples