Computational Biology

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AI Designs Functional CRISPR-Like Nucleases That Work in Cells

Cryo-EM validation shows non-natural enzymes can match or exceed natural activity and open a broader protein design space for genome editing.

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Genome-Scale CRISPRi Atlas Maps Function of Nearly 11,700 Genes in Human Stem Cells

USF Team Unveils AI Framework to Test Immune Recognition Predictions

Living Rat Neurons Trained to Generate Complex Signals

Researchers Deliver 4D Whole-Cell Simulation That Replicates Minimal Bacterium’s Full Life Cycle

CNIO Releases 'Human REPAIRome' Mapping 20,000 DNA Repair Scars

Inhibitory Balance Tunes Theta–Gamma Coupling to Reroute Hippocampal Processing

Algorithm Resolves Neural Progenitor Gene Signature, Ties It to Human Disorders

IISc Study Maps H5N1 Mutations That Raise Human Adaptation Potential

Synthetic Vesicles Sustain 24-Hour Circadian Cycles Across Multiple Days

Researchers Unveil Human-Readable Grammar for Virtual Cell Laboratories

Integrated Biosciences’ Optogenetic Platform Advances Toward Aging and Pan-Antiviral Therapies

DeepMind Launches AlphaGenome to Map Non-Coding DNA Regulation

Artificial Enzymes Designed by Computers Rival Natural Catalysts

Researchers Release AI-Driven Tool for Custom CRISPR-Cas9 Enzyme Design

DeepMind's AlphaFold 3 Goes Open Source, Boosting Drug Discovery

Denmark Unveils Gefion, Its First AI Supercomputer, Powered by Nvidia

AI-Engineered DNA Switches Enable Precise Gene Control in Specific Cells

AI-Powered CREME Revolutionizes Virtual Gene Editing

AI Tool RENAISSANCE Revolutionizes Cell Metabolism Mapping