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Python Metabolite pTOS Curbs Appetite in Mice, Suggesting a New Weight-Loss Pathway

A Nature Metabolism study maps a gut–liver–brain signal from snake feeding, with human relevance still unproven.

Experiments Show Birch Tar Made With Neanderthal Techniques Inhibits Bacteria

Arvinas’ ARV-102 Hits >50% LRRK2 Degradation in Phase 1 Parkinson’s Trial

Alzheimer’s Theory Shifts Focus to Microtubules as Amyloid Beta Crowds Out Tau

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Scientists Pin Down Quinine’s Biosynthetic Pathway, Paving the Way for Engineered Production

Atrogi Begins Dosing in 8-Week Human Study of GRK2-Biased β2 Agonist ATR-258

New RNA Splicing Readout Charts Cancer-Wide Programs, Points to About 120 Potential Targets

Years-Long Gut Microbiome Shifts Linked to Specific Antibiotics in 14,979-Person Swedish Study

Photoreceptor Apoptosis Shown Reversible via Mitophagy in Mouse Models

FDA Approves Leucovorin for Ultra-Rare FOLR1 Folate Disorder, Declines Autism Indication

Xenon to Present Topline X-TOLE2 Phase 3 Results in Focal Onset Seizures at 8 A.M. ET Today

GLP-1 Drugs Tied to Lower Addiction Risk and Harms in Large VA Study

Preliminary Study Links GLP-1 Drugs to Fewer ER Visits in Chronic Migraine

EMA Backs Single-Dose Acoziborole for Gambiense Sleeping Sickness Outside EU

Novo’s Triple-Hormone Obesity Drug UBT251 Hits 19.7% Mean Weight Loss in China Phase 2

Study Identifies Immune Off Switch Behind Why Pain Lasts Longer in Women

Japan Panel Clears iPS Cell Therapies for Heart Failure and Parkinson’s

Lingering IFNγ, Not Fixed Epigenetics, Sustains Macrophage Memory, Study Finds

Ultrasound-Activated Nanobubbles Break Tumor Barriers in Mouse Study

Ancient Romanian Ice Cave Bacterium Resists 10 Modern Antibiotics