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Celecoxib Reprograms Cancer Chromatin to Double Chemotherapy Efficacy in Mice

Mouse model results that doubled chemotherapy efficacy have prompted plans for clinical translation of chromatin-modulating therapy.

Cancer Drugs Reverse Alzheimer’s Pathology in Mice, Advance to Clinical Trials

GLP-1 Weight-Loss Drugs Fail to Boost Fitness and Cause Significant Muscle Loss

Psilocybin Anti-Aging Studies Advance Toward Human Trials

GLP-1 Weight-Loss Drugs Linked to Testosterone Normalization in Men

Frequent Gabapentin Prescriptions Tied to Increased Dementia and Cognitive Impairment Risk

Psilocybin Anti-Aging Efficacy in Cells and Mice Paves Path to Human Trials

Benzaldehyde Disrupts Protein Interface to Thwart Pancreatic Cancer Resistance and Metastasis

Liraglutide Pilot Study Halves Chronic Migraine Days, Paves Way for Randomized Trials

Ambroxol Demonstrates Safety and Neuroprotection Signals in Parkinson’s Dementia Trial

Repurposed Psoriasis Drug Restores Brain Function in Vascular Dementia Mice

Amgen Advances Monthly Obesity Drug to Phase 3 After 20% Weight Loss in Mid-Stage Trial

Researchers Transform Ancient Tomb Fungus Into Potent Antileukemia Compound

Semaglutide Demonstrates Dual Promise in Type 1 Diabetes and Dementia Prevention

Experimental Drug SANA Boosts Fat Thermogenesis to Promote Weight Loss Ahead of Phase 2 Trials

Novo Nordisk’s Amycretin Achieves Up to 24% Weight Loss as It Advances to Phase 3

New Oral β2 Agonist Preserves Muscle in Early Weight-Loss Trials

Liraglutide Cuts Chronic Migraine Days by More Than Half

PDE3 Inhibitors Stimulate Bone Growth in Mice, Offering Potential for Skeletal Disorder Therapies

Cancer Cell Cholesterol Depletion Heightens Hyperthermia Treatment Efficacy