Particle.news
Download on the App Store

WHO Endorses Long-Term GLP-1 Use for Obesity as Indian Ruling Opens Production and Safety Alerts Expand

Global health authorities confront a widening gap between clinical benefits and real-world access.

Overview

  • The World Health Organization issued its first guideline conditionally recommending GLP-1 therapy for adult obesity alongside behavioral care, projecting access to fewer than 10% of eligible people by 2030 and urging pricing and licensing strategies to broaden supply.
  • Australia’s TGA updated product warnings to flag possible mood changes and suicidal ideation with GLP-1s and advised non‑oral or added barrier contraception for four weeks after starting or increasing tirzepatide due to a potential interaction.
  • The Delhi High Court refused Novo Nordisk’s bid for an interim injunction and allowed Dr. Reddy’s to manufacture and export semaglutide, citing a credible patent challenge and characterizing Novo’s filings as double patenting.
  • Novo Nordisk is preparing an India push as Reuters reports Ozempic could launch locally within weeks, a timeline the company has not confirmed.
  • Novo’s oral semaglutide did not slow cognitive decline in Phase 3 Alzheimer’s trials despite modest biomarker shifts, and WADA says GLP-1s remain under monitoring for potential sports misuse with no current ban.