Science ❯ Biology ❯ Molecular Biology

Gene Regulation

MicroRNAs Transcription Factors Long Non-Coding RNAs MicroRNA microRNA microRNA Discovery Regulatory RNA Dosage Compensation MicroRNA Function LUC7 Proteins Cancer Biology Signaling Molecules Aldh1a2 Gene Methylation Pathways Endogenous Retroviruses Epigenetics CDK12/13 SETD2 RNA Sequencing Inflammation RNA Isoforms Chromosome 21 Long Non-Coding RNA Nonsense-Mediated mRNA Decay Zfy Gene Function Transcription TCF/LEF Proteins Non-coding RNAs HOXA10 and TWIST2 Genes Enhancer-Target Interactions Spatial Gene Expression Transcriptional Regulators GDF3 MAP-kinase Pathway Oncogenes Gene Activity

Excess HMGN1 Identified as Driver of Down Syndrome Heart Defects

Researchers trace Down syndrome heart defects to excess HMGN1 using mosaic cell models, CRISPRa screens, with rescue confirmed in mice.

Smooth Muscle lncRNA CARMN Identified as Therapeutic Target for Chronic Limb Ischemia

CDK12/13 Degraders Activate STING-Mediated Immunity and Enhance Checkpoint Therapy

BigHorn Tool Reveals Coordinated Transcriptional and Post-Transcriptional Control by lncRNAs

Preclinical Studies Confirm NKAPL as Lung Cancer Tumor Suppressor, Prompt Demethylation Therapy Development

DynaTag Maps Transcription Factor–DNA Interactions at Single-Cell Resolution and Uncovers Chemotherapy Resistance Dynamics

Study Identifies Four MER11 Subfamilies With Strong Stem Cell Enhancers and 75 New Primate LTR Families

Dormant Vitamin A Gene Switch Restores Ear Regeneration in Mice

Boston University Study Pinpoints Key Domain Driving Melanoma Growth