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Genetic Engineering

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CRISPR Enzyme ThermoCas9 Selectively Cuts Tumor DNA Using Methylation Cues

The work points to a path for cancer tools that home in on epigenetic marks rather than DNA sequence.

Engineered Mini CRISPR Achieves Up to 90% Editing in Human Cells

Lab-Grown ‘T. Rex Leather’ Handbag Unveiled in Amsterdam Ahead of Auction

Engineered Tobacco Plant Produces Five Psychedelic Compounds

PTAB Reaffirms Broad Institute’s Priority for CRISPR-Cas9 in Eukaryotic Cells

Serial Mouse Cloning Fails After 58 Generations as Mutations Pile Up

Toronto Team Synthesizes Functional lncRNAs, Shows Preclinical Anti-Inflammatory Effects

CAR-Astrocyte Gene Therapy Stops Plaques, Halves Amyloid in Alzheimer’s Mice

UCLA Armored CAR T Cells Deliver Local VEGF Blockade, Improve Outcomes in Solid-Tumor Mouse Models

Waterloo Scientists Ready Engineered Tumor‑Eating Bacteria for Preclinical Testing

5,000-Year-Old Cave Bacterium Resists 10 Antibiotics and Inhibits Hospital Pathogens

Ancient Romanian Ice Cave Bacterium Resists 10 Modern Antibiotics

NEJM Study Identifies Viral Protein and Antibody Mutation Behind Rare Vaccine‑Linked Clots

Eli Lilly to Acquire Orna Therapeutics in Up to $2.4 Billion Bet on In Vivo CAR‑T

CRISPR Scan Maps the Strength of Cancer-Driving CTNNB1 Hotspot Mutations

UAE Backs Colossal’s BioVault at Dubai Museum to Bank Genetic Material From Imperiled Species

AI System Designs Entire Viral Genomes as Lab-Built Phage Kills E. coli

Sechenov Researchers Report Non-Viral CRISPR Strategy Aiming to Cure Hepatitis B

Slime-Mold Enzyme Unlocks High-Yield Production of Low-Calorie Sugar Tagatose

Rice Scientists Publish CLASSIC to Massively Expand DNA Circuit Design and Testing