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Immunotherapy

Intratumoral Fc-Optimized CD40 Antibody Achieves Systemic Remissions in Phase 1 Study

Local delivery of 2141-V11 transformed tumors into immune-active sites that triggered systemic responses without systemic inflammation.

AI-Informed Pipeline Accelerates Bi-Specific CAR-T Design and Clears Tumors in Mice

mRNA Neoantigen Vaccine Amplifies Anti-PD-1 Immunity and Suppresses Gastric Cancer Spread in Mice

Off-The-Shelf KRAS Vaccine Yields Robust T-Cell Responses and Survival Benefit

King’s Spin-out Targets Human Trials for Oral Cancer Drug After Promising Mouse Results

CDK12/13 Degraders Activate STING-Mediated Immunity and Enhance Checkpoint Therapy

Researchers Plan Trials to Counteract Sucralose’s Impairment of Cancer Immunotherapy

UF Researchers Develop Universal mRNA Vaccine That Primes Immune System Against Tumors

Exercise-Induced Formate from Gut Microbes Enhances Cancer Immunotherapy

moPepGen Graph Algorithm Quadruples Protein Variant Detection in Tumor Samples

Nagoya University Advances Eva1-Targeted CAR-T Therapy to Preclinical Safety Testing

Anti-CD30 therapy restores PD-1 immunotherapy efficacy in resistant skin cancers

BCG Therapy Reprograms Bone Marrow to Amplify Anti-Cancer Immunity

UCLA Study Finds Antidepressants Boost Immune Response Against Cancer

STAT3 Degraders Poised for Clinical Trials to Combat Immunotherapy Resistance

Cytokine-Enhanced CAR T Cell Therapy Achieves Breakthrough Results in Lymphoma

PLT012 Antibody Advances Toward Clinical Trials as Promising Cancer Immunotherapy

Breakthrough Cell Therapy IMA203 Achieves Durable Responses in Solid Tumors

Experimental Vaccine Keeps Kidney Cancer Patients Cancer-Free for Three Years

Breakthrough CAR-T Cell Therapy Targets Aggressive Brain Tumor