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IFN-γ Receptor Knockout Extends CAR-T Cell Lifespan and Boosts Tumor Combat

It leverages CRISPR/Cas9 disruption of the interferon-γ receptor to boost CAR-T cell durability ahead of planned solid tumor trials.

City of Hope Researchers Map Extrachromosomal DNA to Guide Personalized Brain Cancer Therapies

Cancer Cell Cholesterol Depletion Heightens Hyperthermia Treatment Efficacy

Long-Term Desogestrel Use Linked to Slight Rise in Brain Tumor Risk

Coordinated Loss of the Y Chromosome in Tumors Linked to Poor Cancer Survival

PCSK9 Protein Governs Liver-Versus-Lung Spread of Pancreatic Cancer

Illusia Probe Maps Signaling That Drives Breast Cancer Cell Invasion

Chromosomal Instability Drives Treatment Resistance in Metastatic Cancer

High-Resolution Sequencing Reveals Millions of Mutations in Wilms Tumor and Points to Immunotherapy

UCLA Study Finds Antidepressants Boost Immune Response Against Cancer

Breakthrough 3D Model Reveals How Tumor Clusters Breach Blood Vessels

Study Finds NAD Decline Drives Age-Related CAR-T Cell Therapy Failures

Scientists Identify Key Mechanism Driving Epstein-Barr Virus Spread and Potential Therapeutic Target

Study Identifies Taurine Transporter as Therapeutic Target in Myeloid Leukemias

STAT3 Degraders Poised for Clinical Trials to Combat Immunotherapy Resistance

Study Identifies Lipid-Induced Immune Suppression in Advanced Ovarian Cancer

MIT-Dana-Farber Team Identifies Cryptic Peptides as Novel Targets for Pancreatic Cancer Therapy

Researchers Develop Iron-Activated Molecules to Combat Chemotherapy-Resistant Cancer

Key Cell Type Linked to Early Lung Cancer Development Identified

Plasma-Activated Medium Shows Promise in Treating Rare Synovial Sarcoma