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Cancer Research

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Receptor Pathway Lets Antisense Drugs Escape Endosomes to Silence KRAS in Pancreatic Cancer

The discovery points to using CD44 or EPHA2 as delivery targets together with short, controlled inhibition of cellular repair to raise ASO potency.

Dana-Farber Reports Metabolically Activated Molecular Glue and New Discovery Platform

International Consortium Publishes 665 Validated Patient-Derived Cancer Models

Scientists Identify TRNAU1AP Pathway That Sustains Glioblastoma Stem Cells

Inherited Genes Steer Tumour Evolution, Mouse Study Shows

CAR‑T Cells Targeting GPNMB Eradicate Glioblastoma in Preclinical Models

Spatial Map of Tumor Macrophages Shows Some Eat Cancer While Others Feed It

Tumor Inflammation Drives Early Resistance to KRAS Drugs, Study Shows

Asthma Drug Montelukast Restores Checkpoint Response in Preclinical Cancer Models

Cancer Study Maps Brain Metastasis Switch and Identifies Ibudilast as a Repurposing Candidate

New RNA Splicing Readout Charts Cancer-Wide Programs, Points to About 120 Potential Targets

Oncolytic Viruses Trigger T‑Cell Infiltration and Survival Signals in Early Glioblastoma Trials

Five Protein Mutation Signatures Shape Tumor Immune Visibility

New CAR T Strategy Targets Tumor Macrophages, Triggers Antitumor Immunity in Mice

Study Finds CBD–THC Combination Kills Ovarian Cancer Cells in Lab

Scientists Reveal How Gut Toxin Colibactin Cross-Links DNA in Colorectal Cancer

Crescent, Kelun-Biotech Trade Cancer Asset Rights in Cross-Border Deal as Crescent Secures $185 Million

CRISPR Knockout of NRF2 Reverses Chemotherapy Resistance in Lung Cancer Models

Merck to Buy Cidara for $9.2 Billion to Secure Long-Acting Flu Drug

Study Ties CGRP–RAMP1 Signaling to GI Tumor Growth, Pointing to Repurposed Migraine Therapies