Cancer Huntington's Disease Spinal Muscular Atrophy Hereditary Conditions Kallmann Syndrome Inherited Conditions Alzheimer's Disease Rare Diseases Li-Fraumeni Syndrome Hereditary Diseases Cystic Fibrosis Autism Genetics Neurodevelopmental Disorders Down Syndrome Consanguinity Metabolic Disorders Cardiac Conditions Hutchinson-Gilford Progeria Syndrome Albinism Cousin Marriage Mitochondrial Disease Gene Therapy Werner Syndrome Mitochondrial Diseases Chromosomal Abnormalities Sickle Cell Disease Kidney Disease Barth Syndrome Progeria Fragile X Syndrome Inbreeding Depression Inherited Diabetes Spoan Syndrome LMNA Gene Mutations Mutation Effects Neurofibromatosis DNA Repair Disorders CPS1 Deficiency Rare Genetic Disorders CPSI Deficiency Long COVID Eczema Risk Factors Neurological Disorders Optic Neuropathies Homozygosity Activated PI3-Kinase Delta Syndrome Hermansky-Pudlak Syndrome Inherited Diseases Disease Risk Cellular Dysfunction Gene Regulation GBA1 Gene OTOF Gene Lipoprotein(a) Genetic Mutations Inherited Heart Diseases ALSP Limb Development Parkinson's Disease Genetic Influences on Disease Arteriovenous Malformations Gene-Environment Interactions Speech Disorders Autoinflammatory Disorders Rett Syndrome Harlequin Ichthyosis IKBKG Mutations Color Vision Deficiency Folate Processing Disorders ADSL Deficiency Syndromes Chronic Fatigue Syndrome Immune System ARID1B Mutation 22q.11.2 Deletion Syndrome Tay-Sachs Disease Cousin Marriages Congenital Conditions APOE4 Gene Dementia Genetics Neurodegenerative Diseases Disabilities Multisystemic Smooth Muscle Dysfunction Syndrome Polycystic Kidney Disease Diabetes Risk Factors Heart Diseases G6PD Deficiency Urbach-Wiethe Disease Recessive Diseases Risk Factors Ciliopathies Congenital Disorders C9ORF72 Gene Shared Genetic Variants APOL1 Mutations APOL1 Gene Inherited Eye Conditions Risk Genes Severe Combined Immunodeficiency Stuttering
The work identifies cGAS‑STING as a therapeutic target for disorders caused by defective DNA‑protein crosslink repair.
