Health ❯ Genetics ❯ Genetic Disorders

Down Syndrome

Trisomy 21 Amyloid Precursor Protein Congenital Heart Defects Awareness Initiatives Social Inclusion HMGN1 Gene Awareness and Advocacy

Excess HMGN1 Identified as Driver of Down Syndrome Heart Defects

Researchers trace Down syndrome heart defects to excess HMGN1 using mosaic cell models, CRISPRa screens, with rescue confirmed in mice.

PET Study Finds Early Brain Inflammation in Down Syndrome Linked to Amyloid