The University of California, San Diego (UC San Diego or colloquially, UCSD) is a public land-grant research university in La Jolla, California. Established in 1960 near the pre-existing Scripps Institution of Oceanography, UC San Diego is the southernmost of the ten campuses of the University of California, and offers over 200 undergraduate and graduate degree programs, enrolling 33,096 undergraduate and 9,872 graduate students. The university occupies 2,178 acres (881 ha) near the coast of the Pacific Ocean, with the main campus resting on approximately 1,152 acres (466 ha). UC San Diego consists of twelve undergraduate, graduate and professional schools as well as seven undergraduate residential colleges. It received over 140,000 applications for undergraduate admissions in Fall 2021, making it the second most applied-to university in the United States. UC San Diego Health, the region's only academic health system, provides patient care, conducts medical research and educates future health care professionals at the UC San Diego Medical Center, Hillcrest, Jacobs Medical Center, Moores Cancer Center, Sulpizio Cardiovascular Center, Shiley Eye Institute, Institute for Genomic Medicine, Koman Family Outpatient Pavilion and various express care and urgent care clinics throughout San Diego. The university operates 19 organized research units as well as eight School of Medicine research units, six research centers at Scripps Institution of Oceanography and two multi-campus initiatives. UC San Diego is also closely affiliated with several regional research centers, such as the Salk Institute, the Sanford Burnham Prebys Medical Discovery Institute, the Sanford Consortium for Regenerative Medicine, and the Scripps Research Institute. It is classified among "R1: Doctoral Universities – Very high research activity". According to the National Science Foundation, UC San Diego spent $1.403 billion on research and development in fiscal year 2021, giving it the second-highest R&D spending in the University of California system and the 7th-highest in the nation. UC San Diego is considered one of the United States's Public Ivies. UC San Diego faculty, researchers, and alumni have won 27 Nobel Prizes as well as three Fields Medals, eight National Medals of Science, eight MacArthur Fellowships, and three Pulitzer Prizes. Additionally, of the current faculty, 29 have been elected to the National Academy of Engineering, 70 to the National Academy of Sciences, 45 to the Institute of Medicine and 110 to the American Academy of Arts and Sciences.