Health ❯ Therapeutics ❯ Drug Development

Targeted Therapies

PAR1 Targeting Cell-Specific Targets for Alzheimer's RAP Proteins UNC13A Modulation Mitochondrial Disorders Therapeutics for Alzheimer's Disease Neurodegenerative Disease Treatments Chronic Itch Treatments Metabolic Pathways

3 ARTICLES

last wk.

High-Resolution Structures Show How Muscle Calcium Channels Open Together

Images of RyR1 in native membranes reveal physical contacts that mechanically link neighboring channels and show a site vulnerable to disease and drug targeting.

3 ARTICLES

4mo ago

Review Points to AcCoA‑Driven p300 Acetylation as a Neuronal Route to mTORC1 Overdrive

3 ARTICLES

7mo ago

Itch Protein TRPV4 Also Tells the Brain When to Stop Scratching, Mouse Study Finds

3 ARTICLES

this yr.

Study Ties Obesity to Alzheimer’s Plaque via Fat-Derived Vesicles

3 ARTICLES

last yr.

PAR1 Receptor Drives Lung Lymphatic Remodeling to Accelerate Fluid Clearance