Health ❯ Therapeutics ❯ Drug Development

Targeted Therapies

Chronic Itch Treatments Metabolic Pathways Therapeutics for Alzheimer's Disease Mitochondrial Disorders UNC13A Modulation Cell-Specific Targets for Alzheimer's Neurodegenerative Disease Treatments RAP Proteins PAR1 Targeting

3 ARTICLES

2mo ago

Review Points to AcCoA‑Driven p300 Acetylation as a Neuronal Route to mTORC1 Overdrive

The authors link a leucine‑derived acetyl‑CoA pathway to autophagy failure and protein aggregation and urge targeting upstream metabolic or inflammatory nodes as possible therapeutic directions.

3 ARTICLES

5mo ago

Itch Protein TRPV4 Also Tells the Brain When to Stop Scratching, Mouse Study Finds

3 ARTICLES

10mo ago

Study Ties Obesity to Alzheimer’s Plaque via Fat-Derived Vesicles

3 ARTICLES

last yr.

PAR1 Receptor Drives Lung Lymphatic Remodeling to Accelerate Fluid Clearance