Therapeutics

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Peripheral Immune Blockade Preserves Memory and Brain Tissue in Mouse Tauopathy

An antibody that blocks CXCR3 prevents T cells from entering the brain at its borders, preserves hippocampal tissue, improves memory in mice.

Stroke Remodels Brain Microenvironment to Drive Glioma Growth

Math Model Maps How Copper and Zinc Speed Amyloid‑β Plaque Formation

High-Resolution Structures Show How Muscle Calcium Channels Open Together

Lilly and InnoCare Agree Discovery Pact Valued at Up to $3.35 Billion

Injectable Nanoparticles Restore Light Sensitivity in Blind Retinas

Venetoclax Reduces Intact SIV Reservoir in Macaques

EFHD1 Identified as Driver of Liver Injury in Metabolic Steatohepatitis

Study Links Right-Ventricle Failure and Mitochondrial Changes to Poor Outcomes in PH-HFpEF

Urolithin A Turns On Heart Relaxation Switch and Reverses Lab Signs of HFpEF

Receptor Pathway Lets Antisense Drugs Escape Endosomes to Silence KRAS in Pancreatic Cancer

Study Shows Adult Mouse Brains Replace Lost Astrocytes by Moving Cell Nuclei

Mitochondrial Metabolism Turns On Inflammatory Genes in Aging Cells

Lipoic Acid Trisulfide Strengthens Muscle-Repair Protein in Preclinical Tests

Midlife Remodeling of Human Hippocampus Linked to Microglia Loss and Genome Erosion

Scientists Produce First Structural In‑Cell Map of Influenza A–Host Protein Contacts

Blocking EP2 Restores Macrophage Cleanup and Reverses Aging Signs in Mice

Sleep EEG Shows Myelin Loss Tied to Sleep‑Only Spikes and Slowed REM Oscillations

Epinephrine-Producing C1 Neurons in Brainstem Drive Prolonged Anxiety in Mice

Stem-Cell Dopamine Grafts Found Feasible and Safe at One Year in Parkinson’s Trial