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Psilocybin Reorganizes Brain Activity to Match a Person’s Experience

A Nature paper shows brain patterns shift to track immediate context and subjective state, offering neural markers that could inform therapeutic use.

Definium’s Oral LSD Pill Meets Primary Endpoint in Phase 3 Depression Trial

Single Psilocybin Dose Shows Rapid Antidepressant Effects in Swedish Phase II Trial

Single High Dose of Psilocybin Tied to Lasting Brain Changes and Month-Later Well-Being

Mega-Analysis Maps Common Brain Signature Across Psychedelics

Single IV DMT Dose With Therapy Shows Rapid, Lasting Antidepressant Effect in Phase IIa Trial

Single Psilocybin Dose Rewires Brain-Wide Circuits in Mice, Cell Study Finds

DMT Pushes Brain Away From Critical Balance, Study Finds

Psychedelic DOI Reverses Synaptic Polarity in Claustrum-to-ACC Circuit

Psilocybin Extends Lifespan in Cells and Mice and Paves Way for Human Trials

CBP Seizes 695 Pounds of DMT in Baltimore, Prompting Federal Inquiry

Single Psilocybin Dose Delivers Two-Year Relief From Depression and Anxiety in Cancer Patients