Health ❯ Medicine

Pathology

Tumor Biology Protein Misfolding Disease Mechanisms Cause of Death Medical Examiner Placental Disorders Forensic Pathology Forensic Science Molecular Biology Forensic Analysis Cancer Biology Tumor Microenvironment Contributions Diagnostic Tools Autopsy Vascular Disorders Cerebrovascular Pathology

APOE4 Reprograms Brain Vessel Cells and Impairs Astrocyte Waste Clearance

This preclinical research identifies TGF-β and astrocyte cholesterol-lysosome pathways as drug targets to restore vessel health.

TIE2 Identified as Drug Target in Brain Cavernous Malformations After Mouse Study Stops New Lesions

Tumors Drive Neutrophils Into a CCL3hi State That Fuels Cancer, Study Finds

Tau Neutralizes HSV-1 in Human Neuron Cultures, Pointing to Antiviral Roots of Alzheimer’s Features

ALK7 Identified as Driver of Pancreatic Cancer’s Bloodstream Entry in Preclinical Study