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McMaster Scientists Discover Manikomycin, a New Antibiotic Candidate

It binds the ribosomal E-site to block tRNA translocation, creating a route to overcome existing antibiotic resistance.

CVS Caremark Restores Zepbound and Adds Lilly’s Foundayo to Standard Formularies

Immunovant Shares Surge on Strong Rheumatoid Arthritis Data for IMVT-1402

Oral GLP-1 Weight-Loss Pills Curb Hedonic Eating by Hitting Deep-Brain Circuit in Mice

Five-Target ‘Trojan Horse’ Drug Outperforms Leading Incretins in Obese Diabetic Mice

Clearmind’s AUD Candidate Meets Early Safety Goal as Shares Double

FDA Issues Second Rejection of Replimune’s RP1 Melanoma Therapy

Cholera-Derived Toxin Slows Colorectal Tumors in Mice, Rewiring Local Immunity

Biomea Fusion Prices Equity Offering With Warrants to Raise About $25 Million

FDA Signals Openness to Accelerated Path for Lexeo’s Friedreich’s Ataxia Cardiac Gene Therapy

AI Pinpoints Target of New IBD Antibiotic Enterololin, Speeding Development

Eupraxia Selects 8 mg Dose After Strong EoE Signals, Expands Phase 2b Trial

Liverpool Researchers Report Novltex, a Synthetic Antibiotic Class Against Multidrug-Resistant Bacteria

Novartis to Acquire Tourmaline Bio for $1.4 Billion to Bolster Heart-Drug Pipeline

Terasaki Researchers Debut Human Liver Tumor ‘Embolization-on-a-Chip’ for Embolic Therapy Testing

Autism-Like Behaviors in Mice Traced to Thalamic Circuit as Epilepsy Drug Candidate Reverses Signs

Nektar Therapeutics’ Rezpegaldesleukin Trial Success Sends Shares Up 150%

Acetaminophen Metabolite AM404 Targets Peripheral Nerves to Relieve Pain

UCLA Study Finds Antidepressants Boost Immune Response Against Cancer

New Studies Highlight Ezogabine’s Potential to Redefine Depression Treatment