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‘Trojan-Horse’ Incretin Conjugate Boosts Weight Loss in Mice

The work introduces a targeted delivery strategy that could expand incretin therapy if it proves safe and effective in people.

Clearmind’s AUD Candidate Meets Early Safety Goal as Shares Double

FDA Issues Second Rejection of Replimune’s RP1 Melanoma Therapy

Cholera-Derived Toxin Slows Colorectal Tumors in Mice, Rewiring Local Immunity

BioNTech Raises 2025 Sales Outlook After $1.5 Billion BMS Payment

FDA Approves Lynkuet, a Nonhormonal Pill for Menopausal Hot Flashes

FDA Signals Openness to Accelerated Path for Lexeo’s Friedreich’s Ataxia Cardiac Gene Therapy

Biomea Fusion Prices Equity Offering With Warrants to Raise About $25 Million

AI Pinpoints Target of New IBD Antibiotic Enterololin, Speeding Development

Eupraxia Selects 8 mg Dose After Strong EoE Signals, Expands Phase 2b Trial

Liverpool Researchers Report Novltex, a Synthetic Antibiotic Class Against Multidrug-Resistant Bacteria

Novartis to Acquire Tourmaline Bio for $1.4 Billion to Bolster Heart-Drug Pipeline

Terasaki Researchers Debut Human Liver Tumor ‘Embolization-on-a-Chip’ for Embolic Therapy Testing

Autism-Like Behaviors in Mice Traced to Thalamic Circuit as Epilepsy Drug Candidate Reverses Signs

Merck Completes €3 Billion Springworks Deal in Largest Pharma Acquisition Since 2007

Nektar Therapeutics’ Rezpegaldesleukin Trial Success Sends Shares Up 150%

Acetaminophen Metabolite AM404 Targets Peripheral Nerves to Relieve Pain

Sanofi Acquires Blueprint Medicines for $9.1 Billion

Researchers Identify Brainstem Nerve Cells Driving Semaglutide’s Weight-Loss Effects

UCLA Study Finds Antidepressants Boost Immune Response Against Cancer