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Northwestern Team Reengineers 5-FU Into DNA Nanoparticle That Strikes AML in Mouse Tests

A spherical nucleic acid design uses DNA to ferry the drug into myeloid leukemia cells through scavenger receptors.

Tumor-Induced Nerve Injury Identified as Driver of Anti–PD-1 Resistance

Blocking DKK1 Reprograms Neutrophils and Revives Immunotherapy in Bone Metastases

UCSD Validates STRESS Signature, Pursues Inhibitors to Block Pancreatic Cancer Progression

Universal mRNA Vaccine Eradicates Tumors in Mice and Advances Toward Human Trials

Benzaldehyde Disrupts Protein Interface to Thwart Pancreatic Cancer Resistance and Metastasis

High-Resolution Sequencing Reveals Millions of Mutations in Wilms Tumor and Points to Immunotherapy