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Cancer Biology

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New Study Explains Why BET Drugs Falter by Splitting BRD2 and BRD4 Roles

Targeting each step separately could yield cancer treatments that work more predictably.

Splice-Switching ASO Collapses Oncogenic Circuit in Pancreatic Cancer Models

Preclinical Candidate AVJ16 Blocks IGF2BP1 to Halt Lung Tumor Growth in Models

Glycan-Targeting ‘GlyTR’ Therapy Kills Diverse Cancers in Preclinical Tests

Preclinical Study Highlights HER2 and CD24 as Radiotheranostic Targets in Endometrial Cancer

NF1-Low ER+ Breast Cancers Identified as Likely Responders to CDK4/6 Inhibitors

Science Advances Study Identifies Pentose Phosphate Pathway Vulnerability in MPNST