Research Methodologies

Experimental Techniques Data Analysis RNA Sequencing Animal Studies Experimental Design Computational Biology Imaging Techniques Automated Research Laboratory Techniques CRISPR Technology

HHS Moves to Shift U.S. Biomedical Research From Animal Tests to Human-Based Methods

Allowing nonanimal data for regulatory decisions, HHS seeks to speed drug development by building human-based research capacity.

Low-Input 3D Genome Maps Tie ILC3 Regulatory DNA to Crohn’s Risk

LMU Team Creates Reproducible 3D Human Brain Spheroid That Models Alzheimer’s

Histone Pattern That Activates Genes Is Universal Across Eukaryotes

Study Links Liver Enzyme Genes to Compulsive Cocaine Use in Rats

Single‑Cell Platform Maps How Stromal Barriers Block Antibody Drugs in Solid Tumors

Allen Institute Launches $400 Million Brain Health Accelerator to Turn Brain Maps Into Therapies

ANU Team Publishes RO-iSCAT Nanoscopy Revealing Hidden Cell Bridges

Noninvasive Brain Blood-Flow Markers Align With Alzheimer’s Imaging Signs

Study in Mice Maps Brain–Heart Loop That Worsens Recovery After Heart Attack

Weizmann Scientists Turn Resistance Mutations Into Immunotherapy Targets

Lab Experiments Point to Layered Inner Core Explaining Seismic Anomalies

RPS6KC1 Mutations Identified as Cause of Ultra-Rare Neurodevelopmental Disorder

Open-Access Blood Proteome Atlas Charts Molecular Signatures Across 59 Diseases

Brain-on-a-Chip Reveals BBB Breakdown in Cytokine Storms, Pericytes Restore Integrity

HIV Shown to Reprogram T Cells Into Dormancy That Seeds Latent Reservoirs

Study Finds Blood-Brain Barrier Largely Intact in Key Alzheimer’s Mouse Model

St. Jude Screen Rapidly Optimizes CAST Editors With Higher Precision and Activity

IIT Madras–ICMR Team Identifies ALT1 as New Antifungal Target in Candida Albicans

Small Subset of Newborn Liver Cells Drives Growth, Recasting Pediatric Gene Therapy Timing