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Endocrinology

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Tirzepatide Raises Imaging Signals of Brown Adipose Tissue in Small Randomized Trial

This could mean the drug raises calorie burning at the tissue level; confirmation will require larger trials and tissue analysis.

Early Evidence Suggests GLP‑1 Weight Drugs Can Raise Testosterone and Improve Sperm in Men With Obesity

Five-Target ‘Trojan Horse’ Drug Outperforms Leading Incretins in Obese Diabetic Mice

High-Resolution Map of Pancreatic Cell DNA Methylation Ties ONECUT2 to Type 2 Diabetes

Updated Guidance Urges Test-Guided Use of Vitamin D, Magnesium and Calcium

Common Gene Variants May Blunt GLP-1 Diabetes Drugs for 1 in 10 People

Mouse Study Finds Semaglutide Directly Reprograms Liver Cells to Ease Disease Without Weight Loss

Metformin Lowers Blood Sugar Through Brain Circuit, Mouse Study Finds

Androgen Signaling Drives Lethal Pediatric Ependymoma, Study Finds

Brain Maps of GLP-1 Drugs Point to Paths for Weight Loss Without Nausea

Real-World Study Finds Semaglutide and Tirzepatide Cut Cardiovascular Risk in Type 2 Diabetes

Small Molecule Blocks RAGE–DIAPH1 Pathway, Reduces Diabetic Tissue Damage in Mice

Duke Study Shows Pancreatic Alpha Cells Produce Bioactive GLP-1

Metformin Use Tied to Lower Copper and Iron, Higher Zinc in Human Study

Metformin Requires Hypothalamic Rap1 Inactivation to Lower Blood Sugar

GLP-1 Weight-Loss Drugs Linked to Testosterone Normalization in Men

Brain Neurons Found to Drive Type 2 Diabetes, Independent of Obesity

Study Highlights Distinct Metabolic Effects of Tirzepatide and Semaglutide in Obesity Treatment

AbbVie Enters Obesity Drug Market with $2.2 Billion Licensing Deal

Hormonal Research Suggests Potential Breakthroughs in Anti-Aging Treatments