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Efficacy Studies

Phase 3 Trials Comparative Effectiveness Randomized Controlled Trials HIV-1 ESSENCE-TIMI 73b Trial VYVGART Patient Outcomes Placebo-Controlled Trials Weight Loss in Diabetes AMT-130

FDA Clears Once-Weekly Saphnelo Pen for Self-Injection in Lupus

Phase 3 data showed lower disease activity with safety matching the IV form.

Boehringer’s Survodutide Cuts Body Weight 16.6% in Phase III Trial

AstraZeneca’s Tozorakimab Hits Phase III Goal in COPD, Marking Third Positive Pivotal Trial

Novo’s Triple-Hormone Obesity Drug UBT251 Hits 19.7% Mean Weight Loss in China Phase 2

Roche’s CT-388 Shows Up to 22.5% Placebo-Adjusted Weight Loss in Phase 2 as Phase 3 Nears

Brazil Approves Twice-Yearly Lenacapavir Injection for HIV Prevention

Brazil Authorizes Leqembi for Early-Stage Alzheimer’s Treatment

Zenas' Obexelimab Meets Phase 3 Goals in IgG4-Related Disease With 56% Flare Risk Cut

FDA Approves Vanda’s Nereus, First New Motion Sickness Treatment in Over 40 Years

Dyne’s DMD Drug Hits Primary Endpoint in DELIVER REC, Shows Functional Gains

Protara Reports Strong Interim Phase 2 Results for TARA-002 in Pediatric Lymphatic Malformations

Innovent Says Mazdutide Tops Semaglutide in China Phase 3 Diabetes Trial

Anvisa Approves Mounjaro as First Drug Treatment for Obstructive Sleep Apnea in Adults With Obesity

EMA Panel Recommends Rejecting Rezurock for Chronic Graft-Versus-Host Disease in EU

J&J Myeloma Trial Stopped Early After Tecvayli–Darzalex Shows PFS and OS Benefit

Cannabis Extract VER-01 Eases Chronic Low Back Pain in Phase 3 Trial

Cochrane Review Finds RSV Vaccines Protect Older Adults and Infants Without Raising Serious Risks

Moonlake Shares Plunge on Mixed Phase 3 Results for Hidradenitis Drug

Phase 3 Trials Show Greater Weight Loss With 7.2 mg Injection and 25 mg Oral Semaglutide

Phase 3 Trial Shows Baxdrostat Lowers Blood Pressure by About 10 mmHg in Hard-to-Control Hypertension