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CD70-Targeted HIT Cells Eradicate Solid Tumors in Mice

A peer-reviewed Science study reports mouse tumor clearance using ultra-sensitive receptors that detect very low CD70 levels, prompting plans for a first-in-human safety trial.

New CAR T Strategy Targets Tumor Macrophages, Triggers Antitumor Immunity in Mice

Engineered IgA Antibody Enters Kidney Cysts, Dampens PKD Growth Signals in Mice

First Human Test of Enzyme-Converted Kidney Points to Path for Universal-Type Transplants

Lancet Series Calls for Health-System Overhaul to Deliver New Alzheimer’s Blood Tests and Antibody Drugs

Paclitaxel Reengineered Into Self-Assembling Nanovesicle Shows Strong Preclinical Gains

Early Temferon Trial Shows Engineered Macrophages Reprogram Glioblastoma Niche to Rescue CAR-T Cells

New Blood Test Diagnoses Celiac Disease Without Forcing Gluten Intake

Study uncovers early-life window for in vivo gene therapy of blood stem cells