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Arvinas’ ARV-102 Hits >50% LRRK2 Degradation in Phase 1 Parkinson’s Trial

Positive biomarker readouts plus clean safety underpin a progressive supranuclear palsy study next quarter.

Xenon to Present Topline X-TOLE2 Phase 3 Results in Focal Onset Seizures at 8 A.M. ET Today

Cochrane Review Finds Intermittent Fasting No Better for Weight Loss Than Standard Dieting

Anti-Seizure Drug Levetiracetam Blocks Early Alzheimer’s Protein Production, Study Finds

Study Finds CBD–THC Combination Kills Ovarian Cancer Cells in Lab

Pharvaris’ Oral HAE Drug Deucrictibant Delivers Rapid Relief in Pivotal Phase 3

Immune Cell Stress Switch Implicated in Chemo Neuropathy, With Existing Inhibitors Poised for Tests

Brain Maps of GLP-1 Drugs Point to Paths for Weight Loss Without Nausea

Hydralazine Identified as ADO Inhibitor, Putting Glioblastoma Cells Into Senescence in Lab Study

Reactivated Fetal Gene Triggers Division of Adult Human Heart Cells in Lab

Small Molecule Blocks RAGE–DIAPH1 Pathway, Reduces Diabetic Tissue Damage in Mice

Inhaled CBD Dampens Brain Inflammation in Alzheimer’s Mouse Model

Chemotherapy Drug Paclitaxel Disrupts Brain’s Circadian Clock in Female Mice

Baxdrostat Lowers Blood Pressure in Hard-to-Treat Patients in Phase III Trial

MD Anderson Debuts PreCiSE, a Genome-Wide CRISPR Platform for Primary NK Cells

Tumor-Induced Nerve Injury Identified as Driver of Anti–PD-1 Resistance

Metformin Requires Hypothalamic Rap1 Inactivation to Lower Blood Sugar

Ant2 Inhibitors Rewire T Cells to Strengthen Anti-Tumor Response

Wake Forest Plans Expanded Trials After PET Study Validates Intranasal Insulin Delivery

Benzaldehyde Disrupts Protein Interface to Thwart Pancreatic Cancer Resistance and Metastasis