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Metformin’s Glucose-Lowering Power Traced to the Gut, Not the Liver

The peer-reviewed study links the effect to slowed mitochondrial activity in intestinal cells.

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Five-Target ‘Trojan Horse’ Drug Outperforms Leading Incretins in Obese Diabetic Mice

Common Gene Variants May Blunt GLP-1 Diabetes Drugs for 1 in 10 People

Metformin Lowers Blood Sugar Through Brain Circuit, Mouse Study Finds

Arvinas’ ARV-102 Hits >50% LRRK2 Degradation in Phase 1 Parkinson’s Trial

Xenon to Present Topline X-TOLE2 Phase 3 Results in Focal Onset Seizures at 8 A.M. ET Today

Cochrane Review Finds No Clear Benefit From Daily Aspirin for Colorectal Cancer Prevention

Cochrane Review Finds Intermittent Fasting No Better for Weight Loss Than Standard Dieting

Anti-Seizure Drug Levetiracetam Blocks Early Alzheimer’s Protein Production, Study Finds

Scientific Review Flags He Shou Wu as Multi-Pathway Candidate for Androgenetic Alopecia

Columbia Study Pinpoints How Some Statins May Trigger Muscle Pain

Study Finds CBD–THC Combination Kills Ovarian Cancer Cells in Lab

Pharvaris’ Oral HAE Drug Deucrictibant Delivers Rapid Relief in Pivotal Phase 3

Approved Lymphoma Drug Helps Overcome Resistance in Neuroblastoma Models

Immune Cell Stress Switch Implicated in Chemo Neuropathy, With Existing Inhibitors Poised for Tests

Brain Maps of GLP-1 Drugs Point to Paths for Weight Loss Without Nausea

Hydralazine Identified as ADO Inhibitor, Putting Glioblastoma Cells Into Senescence in Lab Study

Reactivated Fetal Gene Triggers Division of Adult Human Heart Cells in Lab

Small Molecule Blocks RAGE–DIAPH1 Pathway, Reduces Diabetic Tissue Damage in Mice

Inhaled CBD Dampens Brain Inflammation in Alzheimer’s Mouse Model