Tumor Microenvironment Gene Regulation Genetic Variants Immune Response Hypoxia Chromosomal Aberrations Intratumoral Heterogeneity Hormonal Pathways Cell Signaling Cellular Mechanisms Tumor Aggressiveness Targeted Therapy
Researchers have created a multi-neoantigen vaccine blueprint alongside de novo protein binders that achieved precise T cell–mediated melanoma cell killing in vitro, now advancing into animal safety studies.