Health ❯Medicine

Metabolism

Obesity Lipid Metabolism Cell Biology Cellular Metabolism

REDD2 Activation Exacerbates Pancreatic β-Cell Dysfunction and Holds Biomarker Potential

Metabolic stress triggers REDD2 to block mTORC1 signaling, undermining β-cell survival

Dual PIKfyve and KRAS-MAPK Inhibition Eradicates Pancreatic Tumors in Preclinical Models