Therapeutics

Drug Development Cancer Treatment Treatment Strategies Disease Treatment Regenerative Medicine Gene Therapy Pharmacology Antiviral Treatments Immunotherapy Targeted Therapies

Silenced Liver Clock Gene Drives Cancer Cachexia, Reveals New Therapeutic Targets

Reactivating REV-ERBα in mouse models curbs muscle and fat wasting, with patient hepatokine profiles pointing to biomarker potential

In Vivo Prime Editing Corrects AHC Gene Defects and More Than Doubles Mouse Survival

GLUD1 Inhibitor R162 Restores Muscle Function in Duchenne Mouse Model

PAR1 Receptor Drives Lung Lymphatic Remodeling to Accelerate Fluid Clearance

CRISPR Epigenome Editing Controls Inflammation and Tumor Growth in Leukemia Cells

Blocking Imidazole Propionate Receptor Prevents Early Atherosclerosis in Preclinical Models

Psilocybin Anti-Aging Studies Advance Toward Human Trials

Zebrafish Cyclin D Genes Reveal Pathway for Mammalian Hearing Restoration

Integrated Biosciences’ Optogenetic Platform Advances Toward Aging and Pan-Antiviral Therapies

Hundreds of Non-Amyloid Proteins Tied to Age-Related Cognitive Decline

Study Uncovers Cypin’s Synaptic Mechanisms, Fuels Efforts Toward Brain Disorder Treatments

Microglia Replacement Therapy Halts Progression in ALSP Patients

NYU Langone Debuts AI-Based Nuclear Morphometry Pipeline to Quantify Senescent Cells

Human-Specific STING Inhibitors Block Oligomerization Ahead of Clinical Evaluation

Early Temferon Trial Shows Engineered Macrophages Reprogram Glioblastoma Niche to Rescue CAR-T Cells

Scientists Harness Mouth’s GAS6-AXL Pathway to Reduce Skin Scarring

Repurposed Psoriasis Drug Restores Brain Function in Vascular Dementia Mice

Exercise-Activated Gene Discovery Fuels Alzheimer’s Therapy Push

IL-33 Identified as Key Link Between Hepatitis B and Carcinogen-Driven Liver Cancer

Fibroblast ACSL4 Drives Ferroptosis and Offers New IBD Treatment Path