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Immunology

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IFN-γ Receptor Knockout Extends CAR-T Cell Lifespan and Boosts Tumor Combat

It leverages CRISPR/Cas9 disruption of the interferon-γ receptor to boost CAR-T cell durability ahead of planned solid tumor trials.

Nagoya University Advances Eva1-Targeted CAR-T Therapy to Preclinical Safety Testing

Anti-CD30 therapy restores PD-1 immunotherapy efficacy in resistant skin cancers

Ragon Institute Identifies Antibody Features That Restrain Tuberculosis Bacteria

Original COVID-19 Vaccine Sustains Broad Protection Against Delta and Omicron

Study Reveals Thetis Cells as Key to Early-Life Food Allergy Prevention

Early HIV Vaccine Trials Achieve Precise Immune Activation in Humans

STAT3 Degraders Poised for Clinical Trials to Combat Immunotherapy Resistance

Study Identifies Lipid-Induced Immune Suppression in Advanced Ovarian Cancer

HIV Drugs Linked to Reduced Alzheimer’s Risk in Landmark Study

New mRNA Vaccine Strategy Boosts Long-Lasting Immune Memory in Preclinical Study

Study Reveals Key Barriers to TIL Therapy Success in Advanced Lung Cancer

UVA Study Links Immune Biomarkers to Long COVID Lung Damage, Paving Way for Targeted Treatments

Breakthrough Antivenom from Human Antibodies Shows Unmatched Efficacy in Trials

Scientists Develop Broad-Spectrum Snake Antivenom Using Human Antibodies

Immune System Proteins Linked to Mental Health Disorders in Groundbreaking Study

Scientists Develop Rigid Antibodies to Enhance Cancer Immunotherapy

Same-Arm Boosters Found to Enhance Early Vaccine Response

First Human Trial of Type 1 Diabetes Immunotherapy Underway in Australia

New Immune Mechanism Linked to Duodenal Cancer Risk in FAP Patients