Trametinib, sold under the brand name Mekinist among others, is an anticancer medication used for the treatment of melanoma and glioma. It is a MEK inhibitor drug with anti-cancer activity. It inhibits MEK1 and MEK2. It is taken by mouth.
The most common side effects include rash, diarrhea, tiredness, peripheral edema, nausea and acneiform dermatitis. From Wikipedia