Otoferlin is a protein that in humans is encoded by the OTOF gene. It is involved in vesicle membrane fusion, and mutations in the OTOF gene are associated with a genetic form of deafness. From Wikipedia
Karolinska Institutet’s first-in-human use of an adeno-associated virus to deliver OTOF directly into inner ear tissues restored hearing thresholds from 106 to 52 decibels in patients aged 1 to 24 within months without serious adverse reactions