Cardiotrophin-like cytokine factor 1, also known as Novel Neurotrophin-1 or B cell-stimulating factor-3, is a protein that in humans is encoded by the CLCF1 gene. From Wikipedia
Published in Nature Communications, the study shows exercise-induced CLCF1 bolsters muscle mitochondria, shifts bone cell dynamics toward formation over resorption, offering a basis for new therapies targeting age-related decline.