Phosphoglycerate dehydrogenase is an enzyme that catalyzes the chemical reactions 3-phospho-D-glycerate + NAD⁺ 3-phosphonooxypyruvate + NADH + H⁺ 2-hydroxyglutarate + NAD⁺ 2-oxoglutarate + NADH + H⁺ From Wikipedia
The Nature Biotechnology study pinpoints contact sites to guide functional tests and drug‑target discovery.