Taste receptor type 2 member 14 is a protein that in humans is encoded by the TAS2R14 gene. Taste receptors for bitter substances belong to the family of G-protein coupled receptors and are related to class A-like GPCRs. From Wikipedia
Researchers have elucidated the dual activation mechanism of TAS2R14, a key bitter taste receptor, revealing roles for cholesterol and specific intracellular compounds.