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Tumor Biology

Tumor Microenvironment KRAS Mutations Glycan Targeting Pancreatic Ductal Adenocarcinoma PRAME Expression Immune Response Chromosomal Instability Circulating Tumor Cells NECTIN4 Expression RNA-Binding Proteins Targeted Cancer Therapies Therapeutic Targets Tumor Immunology SMARCA4-Deficient Tumors Tumor Growth Patterns Cancer Cell Detection Disease Progression Replication Stress Tumor Eradication Mutation Analysis

Scientists Identify TRNAU1AP Pathway That Sustains Glioblastoma Stem Cells

Disrupting IGF2BP3's stabilization of TRNAU1AP could weaken selenoprotein defenses that help therapy‑resistant tumor stem cells.

PROTEXI Vaccine Redirects COVID‑19 Immune Memory to Target Tumors

New RNA Splicing Readout Charts Cancer-Wide Programs, Points to About 120 Potential Targets

CD70-Targeted HIT Cells Eradicate Solid Tumors in Mice

Study Identifies TSP‑1–CD47 Signal That Drives T‑Cell Exhaustion in Cancer

Engineered CAR-T Cells Target PD-L1 to Deliver IL-12 at Tumors, Showing Solid-Tumor Gains in Mice

Preclinical Candidate AVJ16 Blocks IGF2BP1 to Halt Lung Tumor Growth in Models

Glycan-Targeting ‘GlyTR’ Therapy Kills Diverse Cancers in Preclinical Tests

Genomic Test Predicts Chemotherapy Resistance in Cancer Patients