Pharmacology

Drug Development Psychedelics Drug Mechanisms Psychoactive Substances Drug Safety Cannabinoids Hormones Opioids Synthetic Drugs Psychedelic Research

FDA Grants Tentative Approval for First Generic Twice‑Yearly HIV Prevention Injection

It could allow affordable twice‑yearly PrEP to reach millions in low‑ and middle‑income countries.

Dual EGFR‑MET Therapy Extends Survival in MET‑Overexpressing EGFR‑Mutant Lung Cancer

AstraZeneca’s Sone‑ve Boosts Survival but Fails PFS Goal in Phase III Readout

Arcotatug Tavatecan Extends Survival in CLDN18.2‑Positive Advanced Gastric and GEJ Cancer

Study Finds LSD Speeds Brain Rhythms and Raises Neural Complexity

Novo’s CagriSema Shows 25% Average Weight Loss in Women in Late‑Stage Analysis

Nav1.1 Boost Restores Gamma Rhythm and Memory in Alzheimer’s Mice

Study Finds Glioblastoma Drug Acts on DHODH Not KDM4

DEA Warns of Cychlorphine, an Opioid About 10 Times Stronger Than Fentanyl

FDA Holds Public Hearing as White House Pushes Faster Path for Psychedelic Therapies

New Zealand Approves MDMA for PTSD Under Strict Clinical Controls

SK Biopharmaceuticals Licenses Biohaven’s Opakalim in Deal Worth Up to $795 Million

Hanmi Licenses HM17321 to Genentech in $190 Million Upfront Deal Valued at $2.3 Billion

University of Miami Transfers 1994 Ibogaine IND to Federal Authorities

Man’s Clozapine Dose Became Fatal After He Quit Smoking, Coroner Finds

U.S. Moves to Restrict Potent Kratom Alkaloid as States Expand Emergency Bans

Severe GLP‑1 Overdoses Rise as Online Access and Compounded Vials Expand

GLP‑1 Drugs Linked to Lower Cancer Spread and Death in Large Observational Study

Study Links Liver Enzyme Genes to Compulsive Cocaine Use in Rats

Interpol Sweep Seizes 6.4 Million Fake and Unapproved Medicines Worldwide