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Metabolism

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Experimental RUNX2 Inhibitor Strengthens Bone and Reduces Weight in Menopause Mouse Model

Preclinical data point to a possible new osteoporosis approach that needs human trials to confirm safety and benefit.

Semaglutide Extends Lifespan and Slows Ageing in Older Female Mice

Berkeley Compound TOFA Cuts Fat in Obese Mice by Raising Energy Use

Major Review Finds Lower Protein Intake May Improve Metabolism and Slow Ageing

Scientists Detect Erythrulose Sugar in Cloud Near Milky Way Centre

Ketogenic Diet Boosts Small‑Intestine Tumors While Suppressing Colon Tumors in Mice

Drugs That Induce Hypothermia Cut Stroke Damage in Animals, Fail at Tested Doses in Small Human Trial

Tirzepatide Raises Imaging Signals of Brown Adipose Tissue in Small Randomized Trial

Review Points to AcCoA‑Driven p300 Acetylation as a Neuronal Route to mTORC1 Overdrive

Five-Target ‘Trojan Horse’ Drug Outperforms Leading Incretins in Obese Diabetic Mice

Python Metabolite Reveals New Appetite-Suppressing Pathway in Mice

AI Tool Links Insulin Resistance to Elevated Risk of 12 Cancers in UK Biobank Study

Genome Study Ties Vitamin B1 Biology to Gut Motility, Suggesting Paths to Personalized Care

Blood Metabolite Signature Improves Type 2 Diabetes Risk Prediction

UC San Diego Team Unveils Three-Hit Metabolic Model for Autism

Fatty Food Odors in Pregnancy Linked to Offspring Obesity Risk in Mouse Study

Mouse Study Traces Soybean Oil’s Obesity Link to Liver-Made Oxylipins

Study Reveals Stepwise Assembly of Bacterial Ethanolamine Microcompartments

Lysosome Signals Drive Histone Transfer That Extends Worm Lifespan Across Generations

Blood Metabolites Linked to Daytime Sleepiness in Replicated, Multi-Cohort Study