Robert Downey Jr. Jonathan Majors Anthony Mackie Harrison Ford Chris Evans Hugh Jackman Ryan Reynolds Tom Holland Chris Pratt John Malkovich Wesley Snipes Don Cheadle Mark Ruffalo Chris Hemsworth Dafne Keen Kit Harington Joseph Quinn Tim Blake Nelson Simu Liu Colman Domingo Henry Cavill Sadie Sink Paul Rudd Giancarlo Esposito Mike Colter Florence Pugh Cast Changes Tobey Maguire Gwyneth Paltrow Sebastian Stan Channing Tatum Jeremy Renner Nicolas Cage Marisa Tomei Elizabeth Olsen Tenoch Huerta Kelsey Grammer David Harbour Frank Grillo Jeff Bridges Multiple Roles Benedict Cumberbatch Faran Tahir