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Immunotherapy

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DR5–Lig3 Feedback Loop Explains Why MSI Colorectal Tumors Respond to Immunotherapy

Tumor cell death releases circular DNA that boosts immune sensing, pointing to drug and biomarker strategies for testing.

Single CAR-T Infusion Puts Three Severe Autoimmune Diseases in Remission

IIT Bombay Study Identifies Gentler Enzyme to Retrieve Lab-Grown T Cells for Cancer Therapy

T Cell Receptor Switches From Closed to Open in Native Membrane, Rewriting Activation Model

Nasal Nanodrops Activate STING to Eliminate Glioblastoma in Mice

Engineered Antibody From King’s College London Shows Preclinical Promise Against Hard-to-Treat Breast Cancers

TIM‑3 Triplet Therapy Shows Promise in Immunotherapy‑Resistant Melanoma Models

AI-Informed Pipeline Accelerates Bi-Specific CAR-T Design and Clears Tumors in Mice

CAPGLO Device Promises Rapid, Low-Cost T Cell Harvesting for CAR T Therapy

Study Finds NAD Decline Drives Age-Related CAR-T Cell Therapy Failures

Sheffield Man Becomes Rare Double Stem Cell Donor, Saving Two Lives

King Charles Visits Sydney Cancer Clinic Amidst Ongoing Treatment