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Immunotherapy

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Personalized DNA Vaccine Shows Early Promise in Glioblastoma Trial

The approach targets many tumor-specific mutations at once.

CRISPR CD33-Deleted Stem Cell Transplant Shows Early Promise for AML and MDS

Inhibrx Combo Shows 44% Response vs 21% With Pembrolizumab Alone in First-Line Head and Neck Cancer

New CAR-T Designs Deliver Low-Dose Remissions and Expose a Senescence Risk

Pfizer’s Elrexfio Posts Phase 3 PFS Win Over Standard Multiple Myeloma Regimen

A Meal Primes T Cells Within Hours

Single CAR T Infusion Clears Residual Disease in High-Risk Smoldering Myeloma Trial

First-in-Human SynKIR-110 Shows Safe Profile and Early Activity in Solid Tumors

Experimental Drug Elraglusib Extends Survival in Phase 2 Pancreatic Cancer Trial

Transgene Completes Phase 2 Randomization for Personalized Cancer Vaccine TG4050

Cadonilimab Plus Chemo Delivers Strong Phase 2 Signal in Frontline Endometrial Cancer

FDA Rejects Replimune’s Melanoma Virus Therapy Again for Insufficient Evidence

AstraZeneca’s Imfinzi–Imjudo Regimen Improves Progression-Free Survival in Liver Cancer Trial

Autolus Reports Q4 Loss, Reaffirms 2026 Sales Outlook for AUCATZYL, and Starts AUTO8 Trial

EU Drug Panel Backs Imdylltra for Relapsed Small Cell Lung Cancer

Enlivex Raises $21 Million, Buys 3 Billion RAIN Tokens at a Discount

Climate Change Is Extending Children’s Pollen Seasons in Italy, Driving a Diagnostic Overhaul

Ligand-Based OSM CAR-T Shows Preclinical Efficacy Against Osteosarcoma

EU Grants Conditional Approval for ImmunityBio’s Anktiva in BCG‑Unresponsive Bladder Cancer

DNA Origami Vaccine Scaffold Sharply Focuses HIV Immune Response in Preclinical Study