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Immunotherapy

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Engineered CAR T Cells Targeting MUC16 Control Bladder Tumors in Mice

Direct catheter delivery confined the engineered cells to the bladder, thereby reducing off-target spread, paving the way for clinical testing.

NICE Approves Pembrolizumab with Chemoradiotherapy for Locally Advanced Cervical Cancer

CAR‑T Therapy Lets Highly Sensitized Patients Receive Kidney Transplants

Personalized mRNA Vaccine Halves Five‑Year Melanoma Recurrence Risk

Boehringer’s Zongertinib Wins China Conditional Approval as ASCO Data Show Patient Benefit and Broader Activity

FDA Accepts ImmunityBio Filing to Expand ANKTIVA Use in Bladder Cancer

Personalized DNA Vaccine Shows Strong Immune Response in Early Glioblastoma Study

CRISPR CD33-Deleted Stem Cell Transplant Shows Early Promise for AML and MDS

Inhibrx Combo Shows 44% Response vs 21% With Pembrolizumab Alone in First-Line Head and Neck Cancer

New CAR-T Designs Deliver Low-Dose Remissions and Expose a Senescence Risk

Pfizer’s Elrexfio Posts Phase 3 PFS Win Over Standard Multiple Myeloma Regimen

A Meal Primes T Cells Within Hours

Single CAR T Infusion Clears Residual Disease in High-Risk Smoldering Myeloma Trial

First-in-Human SynKIR-110 Shows Safe Profile and Early Activity in Solid Tumors

Experimental Drug Elraglusib Extends Survival in Phase 2 Pancreatic Cancer Trial

Transgene Completes Phase 2 Randomization for Personalized Cancer Vaccine TG4050

Cadonilimab Plus Chemo Delivers Strong Phase 2 Signal in Frontline Endometrial Cancer

FDA Rejects Replimune’s Melanoma Virus Therapy Again for Insufficient Evidence

AstraZeneca’s Imfinzi–Imjudo Regimen Improves Progression-Free Survival in Liver Cancer Trial

Autolus Reports Q4 Loss, Reaffirms 2026 Sales Outlook for AUCATZYL, and Starts AUTO8 Trial