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Immunology

Cancer Immunology Macrophages Dendritic Cells T Cells Cancer Immunotherapy T Cell Function Tumor Immunology Natural Killer Cells Tumor Microenvironment T Cell Receptors

Researchers Describe Antibody-Directed Xenophagy, a Cell-Intrinsic Pathway That Destroys Invaders

It reveals a TRIM21-driven mechanism that tags antibody-coated pathogens for autophagy to lysosomes.

Spatial Map of Tumor Macrophages Shows Some Eat Cancer While Others Feed It

Scientists Film Skin Macrophages Eating Live Melanoma Cells

Macrophage Swelling Turns On Antiviral Signals and Drives Stronger Inflammation

Preclinical Combo Reprograms Tumor Immunity to Overcome Colorectal Cancer Resistance

New CAR-T Designs Deliver Low-Dose Remissions and Expose a Senescence Risk

A Meal Primes T Cells Within Hours

Barcelona Opens CaixaResearch Institute, First Dedicated Immunology Center in Southern Europe

CIPHER-seq Maps RNA-to-Protein Timing in Single Immune Cells

Tumors Drive Neutrophils Into a CCL3hi State That Fuels Cancer, Study Finds

IIT Bombay Study Identifies Gentler Enzyme to Retrieve Lab-Grown T Cells for Cancer Therapy

New CAR T Strategy Targets Tumor Macrophages, Triggers Antitumor Immunity in Mice

Liver-Targeted mRNA Therapy Rejuvenates T-Cell Immunity in Aging Mice

T Cell Receptor Switches From Closed to Open in Native Membrane, Rewriting Activation Model

GigaTIME AI Converts Routine H&E Slides Into Virtual Spatial Proteomics at Population Scale

Study Pinpoints GPR25 as Switch for Tissue-Resident Memory T Cell Formation

Engineered IgA Antibody Enters Kidney Cysts, Dampens PKD Growth Signals in Mice

Study Identifies TSP‑1–CD47 Signal That Drives T‑Cell Exhaustion in Cancer

Nature Study Maps How Aging Reprograms Memory T Cells, Weakening Vaccine Antibody Responses

Breastfeeding Triggers Long-Lived T Cells That Guard Against Breast Cancer, Nature Study Finds