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Drug Development

Combination Therapy Clinical Trials Targeted Therapies BTK Inhibitors Baxdrostat Combination Therapies GLP-1 Receptor Agonists Therapeutics Ambroxol Natural Compounds

MIT-Led Atlas Maps 31 Neuronal Subtypes in the Human Striatum

The map reveals disease-linked cell signatures that point to targets for follow-up mechanistic work for drug development.

AAN and AHS Update Guideline on Migraine Prevention

CagriSema Combo Lowers Blood Sugar and Drives Bigger Weight Loss Than Semaglutide Alone

Finerenone Slows Kidney Decline in Non‑Diabetic CKD, Trial Shows

AI-Designed Miniproteins Target GPCRs in Nature Study

FDA Approves Baxfendy, First Aldosterone Synthase Inhibitor for Uncontrolled Hypertension

Lithium Chloride Rewires Alzheimer’s-Linked Pathways in Cell Study

Major Review Says New Alzheimer’s Antibodies Offer No Meaningful Benefit

Acoramidis Shows Durable Survival Benefit in ATTR-CM Through 54 Months

Mavacamten Cuts Heart Outflow Obstruction in Teens in First Randomized Trial

NEJM Publication Confirms Phase 3 Win for Brepocitinib in Dermatomyositis

Anti-Seizure Drug Levetiracetam Blocks Early Alzheimer’s Protein Production, Study Finds

Aloe Vera Compound Beta-Sitosterol Identified as Potential Alzheimer’s Drug Lead in Peer-Reviewed In Silico Study

Repurposed Kidney Drug Triggers Egg Development in Small POI Trial, Science Study Reports

Pooled Data Tie Early AE Management to Greater Zolbetuximab Benefit in Gastric/GEJ Cancer

FDA Approves Vanda’s Nereus, First New Motion Sickness Treatment in Over 40 Years

Study Finds CBD–THC Combination Kills Ovarian Cancer Cells in Lab

Ianalumab Plus Eltrombopag Extends Disease Control in Phase 3 ITP Study Published in NEJM

Pirtobrutinib Extends First-Line PFS vs BR and Shows Higher Response Rates Than Ibrutinib in CLL/SLL

Pliant’s PLN-101095 With Keytruda Shows Early Responses in PD-1–Refractory Solid Tumors