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Clinical Research

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Avalo Therapeutics Reports Positive Phase 2 HS Results, Prices $375 Million Offering

The twin updates position Avalo to begin Phase 3 testing of a potential new treatment for hidradenitis suppurativa.

IDEAYA Combo Doubles Progression-Free Survival in Uveal Melanoma Trial

Novo’s Triple-Hormone Obesity Drug UBT251 Hits 19.7% Mean Weight Loss in China Phase 2

Monte Rosa’s MRT-8102 Shows Strong Phase 1 Biomarker Effects, Lifting Shares to 52-Week High

Nektar’s Alopecia Drug Misses Phase 2b Goal as Company Cites Ineligible Patients, Plans Phase 3

Bristol Myers Delays ADEPT-2 Alzheimer’s Psychosis Readout to 2026 After Site Irregularities

Belite Bio’s Tinlarebant Cuts Stargardt Lesion Growth 36% in Phase 3 Trial

AstraZeneca’s Baxdrostat Lowers 24-Hour Systolic BP by 14 mmHg in Phase 3, AHA Presentation Confirms

Lilly’s Oral GLP-1 Orforglipron Beats Farxiga and Placebo in Two Phase 3 Diabetes Trials

Harvard Team Releases PDGrapher, an AI to Predict Gene and Drug Combos That Reverse Diseased Cell States

Jaypirca Delivers Significant PFS Benefit Over Chemoimmunotherapy in First-Line CLL/SLL

Arvinas’ Vepdegestrant Delays Breast Cancer Progression Longer Than Faslodex

Verve-102 Gene-Editing Therapy Shows Promising LDL Cholesterol Reduction in Early Trial

Neumora’s Depression Drug Fails to Meet Goals in Key Phase 3 Trial