Cytokines

APRIL Pathway Interleukin-12 TNFα/NF-κB Signaling

IL-12 Adjuvant in mRNA Vaccines Strengthens CD8+ T Cell Immunity and Broadens Protection

A team led by Christopher Hunter and Anthony Phan used IL-12 encoding mRNA in lipid nanoparticles in mouse models, positioning the platform for cancer immunotherapy and veterinary vaccines.

3 ARTICLES

last mo.

Zigakibart sustains proteinuria remission and stabilizes kidney function over 100-week IgA nephropathy trial