Health ❯ Mental Health ❯ Depression

Major Depressive Disorder

Clinical Trials Treatment Methods Transcranial Direct Current Stimulation Psychedelic Treatment High-Salt Diet Anti-depressant Efficacy Gut Microbiome Treatment Mechanisms Genetic Factors Neural Signaling Pathways

Study Links Depression Fatigue to Distinct Cellular Energy Pattern in Brain and Blood

Researchers report a matching ATP profile in young adults with major depression that aligns with self-reported fatigue.

Single IV DMT Dose With Therapy Shows Rapid, Lasting Antidepressant Effect in Phase IIa Trial

Single IV Dose of DMT Shows Rapid, Lasting Antidepressant Effects in Small Trial

JAMA Psychiatry Study Finds Wearable Sleep-Activity Data Can Forecast Depression Relapse

FDA Approves J&J’s Caplyta for Major Depressive Disorder

Study Finds Women Hold Greater Genetic Risk for Major Depression Than Men

Single Reelin Injection Restores Gut Protein After Stress in Preclinical UVic Study

Soft Drinks Linked to Depression in Women, Study Finds a Microbiome Signal

AbbVie Agrees to Buy Gilgamesh’s Bretisilocin for Up to $1.2 Billion

New Studies Highlight Ezogabine’s Potential to Redefine Depression Treatment

Neumora’s Depression Drug Fails to Meet Goals in Key Phase 3 Trial

AI Algorithm Predicts Antidepressant Efficacy in One Week