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Gene Expression

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Excess HMGN1 Identified as Driver of Down Syndrome Heart Defects

Researchers trace Down syndrome heart defects to excess HMGN1 using mosaic cell models, CRISPRa screens, with rescue confirmed in mice.

Ribosome Stalling Fuels Proteostasis Breakdown in Aging Killifish Brain

Study Identifies Four MER11 Subfamilies With Strong Stem Cell Enhancers and 75 New Primate LTR Families

Benzaldehyde Disrupts Protein Interface to Thwart Pancreatic Cancer Resistance and Metastasis

Maternal Iron Deficiency Triggers Male-to-Female Sex Reversal in Mouse Embryos

UZH Researchers Unveil Real-Time CRISPR Platform to Decode Cancer Cell Evolution

Stanford Researchers Achieve Breakthrough in Precision RNA Delivery for Neuronal Repair